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Disguised as Spider-Man, Mysterio commits a series of crime that makes the webhead public enemy number one. Mysterio then makes his grand appearance and uses the Daily Bugle to taunt Spidey into a confrontation. Spidey meets up with him on top of Brooklyn Bridge and is overwhelmed by Mysterio. Later, Spidey catches up with Mysterio and tricks him into admitting to the crime spree. Spidey defeats Mysterio and clears his name as well as ridiculing the Daily Bugle which had assumed Spidey guilt.